Cardiva Medical has developed an innovative approach to safe, arteriotomy site-specific compression, hemostasis, boomerang effect, secure vascular closure without leaving anything behind in the artery or tissue tract.
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Cardiva Catalyst™ III
Products->US->Cardiva Catalyst™ III
The Protamine Advantage

Cardiva Catalyst III expands beyond Cardiva Catalyst II technology with the addition of a protamine sulfate coating. In heparinized patients, this coating acts to locally neutralize heparin and further aid the body's natural hemostatic process.
The Protamine Advantage
Mechanism of Action: The Body's Response
Cardiva Catalyst III supports the body's natural healing process by enhancing the vessel's inherent natural elastic recoil, tissue apposition, and coagulation.
 
Natural Elastic Recoil
The smooth muscle of the artery relaxes to a pre-dilated state the size of an 18 gauge needle stick.
  Natural Elastic Recoil
 
Tissue apposition
Optimized tissue apposition facilitates vessel healing.
  Tissue apposition
 
Localized protamine
The application of the localized protamine sulfate is designed to neutralize the effects of heparin in the tissue tract at the puncture site.
  Localized protamine
 
Coagulation
The proprietary Catalyst hemostatic coating stimulates both the intrinsic and extrinsic pathways of the coagulation cascade forming fibrin, the backbone of the clot.
  Coagulation
For a copy of the instructions for use, click here ->  IFU 2469 B Instructions for Use for Catalyst III.pdf
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